• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
trpB protein (Methylobacter tundripaludum) - STRING interaction network
"trpB" - Tryptophan synthase beta chain in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (400 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (267 aa)
  0.999
trpC
KEGG- psp-PSPPH_0674 indole-3-glycerol-phosphate synthase; PFAM- Indole-3-glycerol phosphate synthase; Belongs to the TrpC family (266 aa)
 
  0.999
trpF
PFAM- N-(5’phosphoribosyl)anthranilate isomerase (PRAI); KEGG- mca-MCA2496 N-(5’phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family (210 aa)
 
  0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (338 aa)
 
  0.997
Mettu_1450
TIGRFAM- Glutamine amidotransferase of anthranilate synthase; KEGG- prw-PsycPRwf_1153 glutamine amidotransferase of anthranilate synthase; PFAM- Glutamine amidotransferase class-I, C-terminal (214 aa)
 
 
  0.963
Mettu_2356
TIGRFAM- Glutamine amidotransferase of anthranilate synthase; KEGG- mca-MCA2585 anthranilate synthase component II; PFAM- Glutamine amidotransferase class-I, C-terminal (212 aa)
 
 
  0.962
Mettu_1451
KEGG- abm-ABSDF3336 anthranilate synthase component I; PFAM- Chorismate binding, C-terminal; Trp repressor; Anthranilate synthase component I, N-terminal (567 aa)
 
 
  0.942
Mettu_4255
TIGRFAM- Para-aminobenzoate synthase, component I; KEGG- mca-MCA2870 para-aminobenzoate synthase, component I; PFAM- Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal (462 aa)
 
 
  0.938
Mettu_4090
PFAM- Glycosyl transferase, family 3, N-terminal; KEGG- hch-HCH_02544 hypothetical protein (342 aa)
 
 
  0.827
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
      
 
  0.823
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (10%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >