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Mettu_0892 protein (Methylobacter tundripaludum) - STRING interaction network
"Mettu_0892" - FolC bifunctional protein in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mettu_0892FolC bifunctional protein (423 aa)    
Predicted Functional Partners:
Mettu_2918
Dihydropteroate pyrophosphorylase ; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (303 aa)
 
  0.999
Mettu_1997
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
   
 
  0.995
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
  0.973
Mettu_2457
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (167 aa)
 
 
  0.960
fhs
Formyltetrahydrofolate synthetase (557 aa)
   
 
  0.952
Mettu_1611
7,8-dihydroneopterin aldolase ; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (119 aa)
   
 
  0.939
folE
GTP cyclohydrolase I (180 aa)
   
  0.917
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (277 aa)
     
 
  0.901
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta ; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (320 aa)
   
        0.895
Mettu_0893
Sporulation domain-containing protein (320 aa)
   
        0.882
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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