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prfC protein (Methylobacter tundripaludum) - STRING interaction network
"prfC" - Peptide chain release factor 3 in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prfCPeptide chain release factor 3 ; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (531 aa)    
Predicted Functional Partners:
Mettu_0758
Glutamate synthase (Ferredoxin) (1539 aa)
           
  0.844
recA
Recombinase A ; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (345 aa)
         
  0.719
prfA
Peptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (361 aa)
     
 
  0.703
bamB
Outer membrane protein assembly factor BamB ; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (416 aa)
       
 
  0.656
rlmD
23S rRNA(m5U1939)-methyltransferase ; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (444 aa)
           
  0.630
Mettu_2803
Nicotinamide nucleotide transhydrogenase subunit beta ; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (463 aa)
           
  0.606
smpB
Small protein B ; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a "tag peptide", a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tra [...] (161 aa)
       
      0.601
Mettu_0980
PilT protein domain protein (128 aa)
              0.598
Mettu_0979
Antitoxin ; Antitoxin component of a toxin-antitoxin (TA) module (81 aa)
              0.598
Mettu_0031
Ribosomal-protein-alanine acetyltransferase (180 aa)
   
        0.567
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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