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lpxK protein (Methylobacter tundripaludum) - STRING interaction network
"lpxK" - Lipid A 4'-kinase in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lpxKLipid A 4’-kinase ; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA) (333 aa)    
Predicted Functional Partners:
lpxB
Lipid-A-disaccharide synthase ; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (387 aa)
 
 
  0.999
Mettu_3648
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein (419 aa)
 
  0.999
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase ; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (256 aa)
 
   
  0.980
lpxC
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis (307 aa)
 
   
  0.980
lpxD
UDP-3-O-acylglucosamine N-acyltransferase ; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (346 aa)
 
   
  0.980
kdsB
CMP-2-keto-3-deoxyoctulosonic acid synthase ; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (256 aa)
 
   
  0.955
Mettu_0988
MotA/TolQ/ExbB proton channel (204 aa)
 
        0.952
kdsA
Phospho-2-dehydro-3-deoxyoctonate aldolase (277 aa)
 
     
  0.950
Mettu_1253
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase ; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (257 aa)
 
   
  0.933
Mettu_0989
Biopolymer transport protein ExbD/TolR (143 aa)
   
        0.925
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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