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cysG protein (Methylobacter tundripaludum) - STRING interaction network
"cysG" - Siroheme synthase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cysGSiroheme synthase ; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (464 aa)    
Predicted Functional Partners:
Mettu_2437
Uroporphyrinogen III synthase HEM4 (256 aa)
 
  0.999
hemC
Pre-uroporphyrinogen synthase ; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (313 aa)
 
  0.999
Mettu_2779
Sirohydrochlorin ferrochelatase., Precorrin-8X methylmutase (525 aa)
 
  0.998
Mettu_2422
Hydroxymethylbilane synthase ; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (492 aa)
 
  0.994
Mettu_4288
Cobalamin (Vitamin B12) biosynthesis CbiX protein (122 aa)
   
 
  0.990
Mettu_2777
Precorrin-2 C20-methyltransferase (244 aa)
 
 
  0.988
cysI
Sulfite reductase [NADPH] hemoprotein beta-component ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (573 aa)
 
 
  0.983
Mettu_2540
Delta-aminolevulinic acid dehydratase (334 aa)
 
  0.981
Mettu_2774
Precorrin-3B C17-methyltransferase (533 aa)
 
0.978
Mettu_2776
Precorrin-4 C11-methyltransferase (259 aa)
 
   
0.975
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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