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cysG protein (Methylobacter tundripaludum) - STRING interaction network
"cysG" - Siroheme synthase in Methylobacter tundripaludum
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Predicted Interactions
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textmining
co-expression
protein homology
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cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (464 aa)    
Predicted Functional Partners:
Mettu_2437
PFAM- Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; KEGG- nhl-Nhal_3935 uroporphyrinogen III synthase HEM4 (256 aa)
 
  0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (313 aa)
 
  0.997
Mettu_2779
KEGG- hse-Hsero_2654 precorrin-8X methylmutase; PFAM- Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; Cobalamin (vitamin B12) biosynthesis CbiX (525 aa)
 
  0.995
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (573 aa)
 
  0.989
Mettu_2540
KEGG- mca-MCA2793 delta-aminolevulinic acid dehydratase; PFAM- Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family (334 aa)
 
  0.988
Mettu_2418
PFAM- Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; KEGG- mca-MCA2059 nitrite/sulfite reductase protein (550 aa)
 
  0.986
Mettu_2422
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (492 aa)
 
  0.985
Mettu_2774
Precorrin-3B C17-methyltransferase; KEGG- hse-Hsero_2649 bifunctional precorrin-3 methyltransferase/precorrin-6x reductase oxidoreductase; TIGRFAM- Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM- Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; Tetrapyrrole methylase (533 aa)
 
0.968
Mettu_2775
PFAM- Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG- ddr-Deide_2p01620 cobalamin biosynthesis protein CbiG (254 aa)
 
  0.967
Mettu_4288
PFAM- Cobalamin (vitamin B12) biosynthesis CbiX; KEGG- ant-Arnit_0389 cobalamin (vitamin B12) biosynthesis protein CbiX (122 aa)
   
 
  0.962
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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