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rplB protein (Methylobacter tundripaludum) - STRING interaction network
"rplB" - 50S ribosomal protein L2 in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rplB50S ribosomal protein L2 ; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (275 aa)    
Predicted Functional Partners:
rplV
50S ribosomal protein L22 ; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (111 aa)
  0.999
rpsS
30S ribosomal protein S19 ; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (90 aa)
  0.999
rplC
50S ribosomal protein L3 ; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (216 aa)
 
  0.999
rplP
50S ribosomal protein L16 ; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (137 aa)
 
  0.999
rplN
50S ribosomal protein L14 ; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (122 aa)
 
  0.999
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (223 aa)
 
  0.999
rplW
50S ribosomal protein L23 ; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (99 aa)
 
  0.999
rplE
50S ribosomal protein L5 ; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (179 aa)
 
  0.999
rplD
50S ribosomal protein L4 ; Forms part of the polypeptide exit tunnel (206 aa)
 
  0.999
rplA
50S ribosomal protein L1 ; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (231 aa)
 
  0.999
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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