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prs protein (Methylobacter tundripaludum) - STRING interaction network
"prs" - Phosphoribosyl pyrophosphate synthase in Methylobacter tundripaludum
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prsPhosphoribosyl pyrophosphate synthase ; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (317 aa)    
Predicted Functional Partners:
glmU
Bifunctional protein GlmU ; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (488 aa)
   
  0.964
purF
Glutamine phosphoribosylpyrophosphate amidotransferase ; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (502 aa)
   
  0.933
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (528 aa)
 
   
  0.917
Mettu_1370
Transketolase ; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (661 aa)
     
 
  0.914
Mettu_1489
Ribose-phosphate pyrophosphokinase (292 aa)
   
   
 
0.911
Mettu_1881
Phosphoriboisomerase A ; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate (217 aa)
   
 
  0.907
pyrE
Orotate phosphoribosyltransferase ; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (214 aa)
     
 
  0.903
Mettu_1557
Phosphoglucomutase (544 aa)
     
  0.895
hisG
ATP phosphoribosyltransferase ; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (209 aa)
   
 
  0.892
Mettu_1833
Phosphoglucomutase (880 aa)
   
 
  0.889
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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