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prs protein (Methylobacter tundripaludum) - STRING interaction network
"prs" - Ribose-phosphate pyrophosphokinase in Methylobacter tundripaludum
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Known Interactions
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Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (317 aa)    
Predicted Functional Partners:
glmU
Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (488 aa)
   
  0.935
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
 
   
  0.917
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis; Belongs to the PTH family (189 aa)
 
      0.894
Mettu_1297
Pyruvate dehydrogenase (Acetyl-transferring); KEGG- rpx-Rpdx1_1427 transketolase central region; PFAM- Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; overlaps another CDS with the same product name (356 aa)
     
  0.892
Mettu_1370
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (661 aa)
   
  0.890
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (502 aa)
   
  0.871
Mettu_0443
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (803 aa)
   
 
  0.866
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (292 aa)
 
   
  0.855
Mettu_1881
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate (217 aa)
     
 
  0.839
Mettu_2831
TIGRFAM- Nucleoside diphosphate pyrophosphatase; KEGG- mca-MCA1477 hypothetical protein; PFAM- NUDIX hydrolase domain (198 aa)
   
  0.825
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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