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prfA protein (Methylobacter tundripaludum) - STRING interaction network
"prfA" - Peptide chain release factor 1 in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prfAPeptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (361 aa)    
Predicted Functional Partners:
prmC
Protein-glutamine N-methyltransferase PrmC ; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif (284 aa)
 
  0.999
hemA
Glutamyl-tRNA reductase ; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (419 aa)
 
   
  0.968
prmB
N5-glutamine methyltransferase PrmB ; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (310 aa)
 
 
  0.967
frr
Ribosome-releasing factor ; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (185 aa)
 
 
  0.954
lepA
Ribosomal back-translocase LepA ; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (599 aa)
 
   
  0.903
rplD
50S ribosomal protein L4 ; Forms part of the polypeptide exit tunnel (206 aa)
 
  0.886
prs
Phosphoribosyl pyrophosphate synthase ; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (317 aa)
 
 
  0.886
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (142 aa)
 
 
  0.868
rplQ
50S ribosomal protein L17 (125 aa)
 
 
  0.863
prfB
Peptide chain release factor 2 ; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (365 aa)
   
0.855
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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