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fhs protein (Methylobacter tundripaludum) - STRING interaction network
"fhs" - Formyltetrahydrofolate synthetase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fhsFormyltetrahydrofolate synthetase (557 aa)    
Predicted Functional Partners:
Mettu_3646
Methenyltetrahydrofolate cyclohydrolase (209 aa)
 
   
  0.982
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
  0.979
purH
Bifunctional purine biosynthesis protein PurH (535 aa)
   
 
  0.961
Mettu_0892
FolC bifunctional protein (423 aa)
   
 
  0.952
purL
Formylglycinamide ribonucleotide amidotransferase ; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1289 aa)
   
   
  0.928
Mettu_3697
Aminomethyltransferase ; The glycine cleavage system catalyzes the degradation of glycine (360 aa)
   
 
  0.915
Mettu_1405
Methionine synthase (1226 aa)
   
 
  0.900
Mettu_1997
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
   
 
  0.899
purM
Phosphoribosyl-aminoimidazole synthetase (347 aa)
   
 
  0.892
purD
Phosphoribosylglycinamide synthetase (426 aa)
   
 
  0.886
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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