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proC protein (Methylobacter tundripaludum) - STRING interaction network
"proC" - Pyrroline-5-carboxylate reductase in Methylobacter tundripaludum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline (275 aa)    
Predicted Functional Partners:
Mettu_3740
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family (1032 aa)
     
  0.961
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate; Belongs to the gamma-glutamyl phosphate reductase family (418 aa)
 
 
  0.900
Mettu_1590
PFAM- Protein of unknown function YGGT; KEGG- mca-MCA1534 YGGT family protein (191 aa)
   
        0.890
Mettu_1591
UPF0235 protein Mettu_1591; PFAM- Protein of unknown function DUF167; manually curated; TIGRFAM- Conserved hypothetical protein CHP00251; KEGG- avn-Avin_03050 hypothetical protein; HAMAP- Protein of unknown function DUF167; Belongs to the UPF0235 family (100 aa)
              0.889
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate (373 aa)
 
 
  0.878
Mettu_1685
Pyridoxal phosphate homeostasis protein; Pyridoxal 5’-phosphate (PLP)-binding protein, which is involved in PLP homeostasis (227 aa)
        0.869
Mettu_0649
KEGG- ftn-FTN_1444 ornithine cyclodeaminase; PFAM- Ornithine cyclodeaminase/mu-crystallin (336 aa)
       
  0.817
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
   
   
  0.795
Mettu_2477
TIGRFAM- Peptidase S33, proline iminopeptidase 1; KEGG- mca-MCA1737 proline iminopeptidase; PFAM- Alpha/beta hydrolase fold-1; Belongs to the peptidase S33 family (315 aa)
   
 
    0.788
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (151 aa)
            0.762
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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