• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Mettu_1610 protein (Methylobacter tundripaludum) - STRING interaction network
"Mettu_1610" - KEGG: mca:MCA2987 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mettu_1610KEGG- mca-MCA2987 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (166 aa)    
Predicted Functional Partners:
Mettu_1611
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (119 aa)
   
 
  0.986
Mettu_2918
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (303 aa)
 
  0.974
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (367 aa)
   
 
  0.916
Mettu_2457
TIGRFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG- mca-MCA2313 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (167 aa)
   
 
 
0.812
Mettu_1405
Methionine synthase; TIGRFAM- 5-methyltetrahydrofolate--homocysteine methyltransferase; KEGG- mca-MCA1545 B12-dependent methionine synthase; PFAM- Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; Vitamin B12 dependent methionine synthase, activation region (1226 aa)
         
  0.783
plsY
Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (195 aa)
   
        0.749
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5’-adenylate (BirA-bio- 5’-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon (332 aa)
 
     
  0.660
Mettu_0892
FolC bifunctional protein; TIGRFAM- Folylpolyglutamate synthetase; KEGG- mca-MCA2492 folylpolyglutamate synthase/dihydrofolate synthase; PFAM- Mur ligase, central; Mur ligase, C-terminal (423 aa)
 
 
  0.625
Mettu_0901
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (361 aa)
   
   
  0.597
Mettu_2825
KEGG- alv-Alvin_2084 chorismate mutase; TIGRFAM- Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM- Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT (361 aa)
            0.536
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (13%) [HD]