Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
PFAM- Abortive infection protein; KEGG- mca-MCA0527 hypothetical protein (291 aa)
Predicted Functional Partners:
Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (253 aa)
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily (450 aa)
KEGG- hypothetical protein (579 aa)
KEGG- mca-MCA1689 hypothetical protein (428 aa)
KEGG- mmb-Mmol_1761 hypothetical protein (101 aa)
KEGG- mca-MCA0965 hypothetical protein (193 aa)
PFAM- General secretion pathway protein M; KEGG- mca-MCA1122 general secretion pathway protein, putative (195 aa)