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STRINGSTRING
cca protein (Methylobacter tundripaludum) - STRING interaction network
"cca" - Multifunctional CCA protein in Methylobacter tundripaludum
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ccaMultifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases (407 aa)    
Predicted Functional Partners:
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (692 aa)
   
  0.936
rnr
Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs (746 aa)
   
  0.933
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs; Belongs to the RNase E/G family. RNase E subfamily (819 aa)
     
  0.904
Mettu_2466
Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain (484 aa)
     
  0.889
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
   
 
    0.874
rnt
Ribonuclease T; Trims short 3’ overhangs of a variety of RNA species, leaving a one or two nucleotide 3’ overhang. Responsible for the end-turnover of tRNA- specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (207 aa)
 
 
  0.823
Mettu_2547
KEGG- alv-Alvin_2537 endoribonuclease L-PSP; TIGRFAM- YjgF-like protein; PFAM- Endoribonuclease L-PSP (134 aa)
       
    0.799
Mettu_4019
Uncharacterized protein; PFAM- Archease, tRNA m5C methyltransferase chaperone; KEGG- tgr-Tgr7_1949 protein of unknown function DUF101 (144 aa)
 
            0.768
Mettu_0386
Uncharacterized protein; KEGG- aeh-Mlg_1716 beta-lactamase superfamily hydrolase (649 aa)
   
 
  0.721
Mettu_1646
Probable membrane transporter protein; PFAM- Protein of unknown function DUF81; KEGG- dma-DMR_18860 hypothetical membrane protein (263 aa)
              0.714
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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