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hisB protein (Methylobacter tundripaludum) - STRING interaction network
"hisB" - Imidazoleglycerol-phosphate dehydratase in Methylobacter tundripaludum
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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hisBImidazoleglycerol-phosphate dehydratase (208 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase ; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (436 aa)
 
  0.999
Mettu_1664
ImGP synthase subunit HisH ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (214 aa)
 
 
  0.999
hisF
ImGP synthase subunit HisF ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (257 aa)
 
 
  0.999
Mettu_0176
Imidazole acetol-phosphate transaminase (362 aa)
 
  0.999
Mettu_1474
ImGP synthase subunit HisH ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (221 aa)
 
 
  0.999
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (244 aa)
   
  0.997
Mettu_2826
Imidazole acetol-phosphate transaminase (386 aa)
 
  0.997
hisI
Phosphoribosyl-AMP cyclohydrolase ; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (130 aa)
 
 
  0.994
hisG
ATP phosphoribosyltransferase ; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (209 aa)
 
   
  0.989
hisE
Phosphoribosyl-ATP pyrophosphatase (105 aa)
 
 
  0.982
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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