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hisI protein (Methylobacter tundripaludum) - STRING interaction network
"hisI" - Phosphoribosyl-AMP cyclohydrolase in Methylobacter tundripaludum
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (130 aa)    
Predicted Functional Partners:
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM- Histidine biosynthesis; TIGRFAM- Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP- 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG- mca-MCA2803 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (244 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (257 aa)
 
  0.999
hisE
TIGRFAM- Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP- Phosphoribosyl-ATP pyrophosphatase; KEGG- mca-MCA2800 phosphoribosyl-ATP pyrophosphatase; PFAM- Phosphoribosyl-ATP pyrophosphohydrolase (105 aa)
   
  0.999
hisB
HAMAP- Imidazoleglycerol-phosphate dehydratase; KEGG- psa-PST_4090 imidazoleglycerol-phosphate dehydratase; PFAM- Imidazoleglycerol-phosphate dehydratase (208 aa)
 
  0.998
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (209 aa)
 
 
  0.993
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (436 aa)
 
 
  0.990
Mettu_1664
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (214 aa)
 
 
  0.987
Mettu_1474
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (221 aa)
 
 
  0.972
Mettu_0176
PFAM- Aminotransferase, class I/II; TIGRFAM- Histidinol-phosphate aminotransferase; HAMAP- Histidinol-phosphate aminotransferase; KEGG- nhl-Nhal_0352 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (362 aa)
 
 
  0.922
Mettu_1748
PFAM- Aminotransferase, class I/II; KEGG- sua-Saut_0088 class I/II aminotransferase (339 aa)
 
 
  0.905
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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