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metG protein (Methylobacter tundripaludum) - STRING interaction network
"metG" - Methionine--tRNA ligase in Methylobacter tundripaludum
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily (672 aa)    
Predicted Functional Partners:
pheS
TIGRFAM- Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP- Phenylalanyl-tRNA synthetase alpha chain; KEGG- mca-MCA0697 phenylalanyl-tRNA synthetase subunit alpha; PFAM- Phenylalanyl-tRNA synthetase alpha chain; Phenylalanyl-tRNA synthetase, class II, N-terminal; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily (339 aa)
   
  0.996
argS
Arginine--tRNA ligase; TIGRFAM- Arginyl-tRNA synthetase, class Ic; HAMAP- Arginyl-tRNA synthetase, class Ic; KEGG- mca-MCA3089 arginyl-tRNA synthetase (586 aa)
   
  0.959
leuS
Leucine--tRNA ligase; TIGRFAM- Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; KEGG- tgr-Tgr7_2279 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (832 aa)
   
  0.959
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as ’pretransfer’ editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated ’posttransfer’ editing and involves deacy [...] (569 aa)
   
  0.955
thrS
Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (635 aa)
   
 
  0.954
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
   
 
  0.951
lysS
Lysine--tRNA ligase; PFAM- Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM- Lysyl-tRNA synthetase, class II; HAMAP- Lysyl-tRNA synthetase; KEGG- nhl-Nhal_2437 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family (499 aa)
 
  0.949
pheT
TIGRFAM- Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; HAMAP- Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; KEGG- mca-MCA0698 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (791 aa)
   
 
  0.949
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (943 aa)
   
  0.943
tyrS
Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily (398 aa)
   
  0.938
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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