STRINGSTRING
gmk protein (Methylobacter tundripaludum) - STRING interaction network
"gmk" - GMP kinase in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGMP kinase ; Essential for recycling GMP and indirectly, cGMP (204 aa)    
Predicted Functional Partners:
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (528 aa)
     
 
  0.995
ndk
Nucleoside-2-P kinase ; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (143 aa)
     
  0.990
Mettu_0730
Serine/threonine protein kinase (448 aa)
   
  0.987
rpoZ
Transcriptase subunit omega ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta’ subunit thereby facilitating its interaction with the beta and alpha subunits (81 aa)
   
   
  0.967
Mettu_1869
Inosine-5’-monophosphate dehydrogenase (488 aa)
   
 
  0.950
Mettu_2548
(P)ppGpp synthetase I, SpoT/RelA ; In eubacteria ppGpp (guanosine 3’-diphosphate 5-’ diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (723 aa)
   
 
  0.943
Mettu_1170
Protein serine/threonine phosphatase (578 aa)
 
  0.933
Mettu_3579
Phosphoribosyltransferase (179 aa)
   
 
  0.920
apt
Adenine phosphoribosyltransferase ; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (171 aa)
   
 
  0.918
Mettu_4341
Pyruvate kinase (484 aa)
   
 
  0.908
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (13%) [HD]