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ribA protein (Methylobacter tundripaludum) - STRING interaction network
"ribA" - GTP cyclohydrolase-2 in Methylobacter tundripaludum
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ribAGTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5’-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family (202 aa)    
Predicted Functional Partners:
Mettu_0901
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (361 aa)
  0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family (158 aa)
 
 
  0.997
Mettu_0902
Riboflavin synthase, alpha subunit; TIGRFAM- Lumazine-binding protein; KEGG- tgr-Tgr7_1560 riboflavin synthase, alpha subunit; PFAM- Lumazine-binding protein (218 aa)
  0.986
folE
PFAM- GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM- GTP cyclohydrolase I; HAMAP- GTP cyclohydrolase I; KEGG- mca-MCA1670 GTP cyclohydrolase I (180 aa)
 
 
 
  0.947
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (367 aa)
 
 
0.911
Mettu_0647
KEGG- mca-MCA1870 riboflavin biosynthesis protein RibD domain-containing protein (280 aa)
   
  0.864
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (143 aa)
     
  0.807
Mettu_0233
Multi-sensor signal transduction multi-kinase; PFAM- ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase-like domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG- putative phytochrome sensor protein; SMART- ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region (1710 aa)
       
    0.801
Mettu_3162
Histidine kinase; TIGRFAM- PAS; PFAM- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; PAS fold-3; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG- azo-azo2450 putative two-component system sensor protein; SMART- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; PAS; PAC motif (1278 aa)
   
 
    0.793
Mettu_1576
Outer membrane adhesin like proteiin; TIGRFAM- VCBS repeat domain; PFAM- Putative Ig; KEGG- cch-Cag_1242 VCBS; SMART- Dystroglycan-type cadherin-like (6210 aa)
       
    0.790
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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