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polA protein (Methylobacter tundripaludum) - STRING interaction network
"polA" - DNA polymerase I in Methylobacter tundripaludum
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)    
Predicted Functional Partners:
Mettu_1953
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (366 aa)
 
  0.996
Mettu_1083
KEGG- pmy-Pmen_0549 sporulation domain-containing protein; PFAM- Sporulation/cell division region, bacteria; SMART- ATPase, AAA+ type, core (628 aa)
   
  0.989
Mettu_0829
TIGRFAM- DNA polymerase III, delta prime subunit; KEGG- mca-MCA1995 DNA polymerase III, delta prime subunit (352 aa)
 
  0.985
Mettu_3850
DNA-directed DNA polymerase; SMART- Polymerase/histidinol phosphatase, N-terminal; TIGRFAM- DNA polymerase III, alpha subunit; KEGG- mca-MCA1286 DNA polymerase III, alpha subunit; PFAM- Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type (1164 aa)
 
  0.983
Mettu_0058
SMART- Helicase, ATP-dependent, c2 type; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; KEGG- mca-MCA1991 ATP-dependent helicase, putative (645 aa)
 
  0.976
Mettu_3680
KEGG- ttu-TERTU_1636 ribonucleotide reductase, alpha subunit (254 aa)
   
  0.975
Mettu_3679
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (716 aa)
   
  0.975
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (345 aa)
 
  0.975
Mettu_2674
TIGRFAM- DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM- RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG- mca-MCA1868 ATP-dependent DNA helicase RecQ; SMART- DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain (712 aa)
   
  0.969
Mettu_3852
Multi-sensor hybrid histidine kinase; TIGRFAM- PAS; PFAM- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; PAS fold-4; Signal transduction response regulator, receiver region; KEGG- bxe-Bxe_B1311 PAS/PAC sensor hybrid histidine kinase; SMART- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region (872 aa)
   
 
  0.962
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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