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rtcA protein (Methylobacter tundripaludum) - STRING interaction network
"rtcA" - RNA 3'-terminal phosphate cyclase in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rtcARNA 3’-terminal phosphate cyclase ; Catalyzes the conversion of 3’-phosphate to a 2’,3’- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3’P to produce RNA- N3’PP5’A; (C) and attack of the adjacent 2’-hydroxyl on the 3’- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (353 aa)    
Predicted Functional Partners:
rpsD
30S ribosomal protein S4 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (206 aa)
     
    0.897
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (528 aa)
     
        0.877
Mettu_2218
Putative uncharacterized protein (83 aa)
              0.864
rtcB
RNA-splicing ligase RtcB (476 aa)
 
   
  0.839
rpsI
30S ribosomal protein S9 (131 aa)
   
    0.830
Mettu_4189
ATP-dependent helicase HrpA (1315 aa)
     
    0.824
rpsG
30S ribosomal protein S7 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (156 aa)
     
    0.814
rpsQ
30S ribosomal protein S17 ; One of the primary rRNA binding proteins, it binds specifically to the 5’-end of 16S ribosomal RNA (87 aa)
     
    0.811
rpsO
30S ribosomal protein S15 ; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (89 aa)
     
    0.795
rpsK
30S ribosomal protein S11 ; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (128 aa)
     
    0.784
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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