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pyrE protein (Methylobacter tundripaludum) - STRING interaction network
"pyrE" - Orotate phosphoribosyltransferase in Methylobacter tundripaludum
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (214 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily (241 aa)
   
 
  0.999
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (337 aa)
   
 
  0.994
carA
TIGRFAM- Carbamoyl phosphate synthase, small subunit; KEGG- mmw-Mmwyl1_4035 carbamoyl phosphate synthase small subunit; PFAM- Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family (376 aa)
   
   
  0.911
Mettu_3479
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate (337 aa)
   
 
  0.893
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (243 aa)
   
 
  0.877
carB
TIGRFAM- Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG- mca-MCA1852 carbamoyl-phosphate synthase, large subunit; PFAM- Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Belongs to the CarB family (1072 aa)
   
   
  0.862
Mettu_1176
KEGG- pna-Pnap_4658 hypothetical protein (340 aa)
   
   
  0.860
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
 
   
  0.859
Mettu_3793
PFAM- Oxidoreductase FAD/NAD(P)-binding; KEGG- mca-MCA0335 hypothetical protein (1230 aa)
       
  0.839
pyrB
PFAM- Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM- Aspartate carbamoyltransferase, eukaryotic; HAMAP- Aspartate carbamoyltransferase; KEGG- mca-MCA2333 aspartate carbamoyltransferase catalytic subunit; Belongs to the ATCase/OTCase family (321 aa)
   
   
  0.838
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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