| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mettu_2465 | Mettu_2466 | Mettu_2465 | Mettu_2466 | TIGRFAM- Maf-like protein; HAMAP- Maf-like protein; KEGG- cja-CJA_2814 septum formation protein Maf; PFAM- Maf-like protein | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | 0.909 |
| Mettu_2465 | pnp | Mettu_2465 | Mettu_4208 | TIGRFAM- Maf-like protein; HAMAP- Maf-like protein; KEGG- cja-CJA_2814 septum formation protein Maf; PFAM- Maf-like protein | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction | 0.817 |
| Mettu_2465 | rlmH | Mettu_2465 | Mettu_2464 | TIGRFAM- Maf-like protein; HAMAP- Maf-like protein; KEGG- cja-CJA_2814 septum formation protein Maf; PFAM- Maf-like protein | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family | 0.889 |
| Mettu_2466 | Mettu_2465 | Mettu_2466 | Mettu_2465 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | TIGRFAM- Maf-like protein; HAMAP- Maf-like protein; KEGG- cja-CJA_2814 septum formation protein Maf; PFAM- Maf-like protein | 0.909 |
| Mettu_2466 | cca | Mettu_2466 | Mettu_1645 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | 0.889 |
| Mettu_2466 | pcnB | Mettu_2466 | Mettu_2456 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Poly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control | 0.863 |
| Mettu_2466 | pnp | Mettu_2466 | Mettu_4208 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction | 0.886 |
| Mettu_2466 | rlmH | Mettu_2466 | Mettu_2464 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family | 0.889 |
| Mettu_2466 | rnd | Mettu_2466 | Mettu_4258 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribonuclease D; Exonuclease involved in the 3’ processing of various precursor tRNAs. Initiates hydrolysis at the 3’-terminus of an RNA molecule and releases 5’-mononucleotides; Belongs to the RNase D family | 0.800 |
| Mettu_2466 | rne | Mettu_2466 | Mettu_3849 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs; Belongs to the RNase E/G family. RNase E subfamily | 0.827 |
| Mettu_2466 | rnr | Mettu_2466 | Mettu_2572 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs | 0.831 |
| Mettu_2466 | rnt | Mettu_2466 | Mettu_2881 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribonuclease T; Trims short 3’ overhangs of a variety of RNA species, leaving a one or two nucleotide 3’ overhang. Responsible for the end-turnover of tRNA- specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis | 0.769 |
| Mettu_2466 | rph | Mettu_2466 | Mettu_2039 | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | Ribonuclease PH; Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates | 0.851 |
| cca | Mettu_2466 | Mettu_1645 | Mettu_2466 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Ribonuclease, Rne/Rng family; KEGG- mca-MCA0379 ribonuclease G; TIGRFAM- Ribonuclease E/G; PFAM- RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain | 0.889 |
| cca | pcnB | Mettu_1645 | Mettu_2456 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Poly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control | 0.652 |
| cca | pnp | Mettu_1645 | Mettu_4208 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction | 0.936 |
| cca | rnd | Mettu_1645 | Mettu_4258 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Ribonuclease D; Exonuclease involved in the 3’ processing of various precursor tRNAs. Initiates hydrolysis at the 3’-terminus of an RNA molecule and releases 5’-mononucleotides; Belongs to the RNase D family | 0.552 |
| cca | rne | Mettu_1645 | Mettu_3849 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs; Belongs to the RNase E/G family. RNase E subfamily | 0.904 |
| cca | rnr | Mettu_1645 | Mettu_2572 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs | 0.933 |
| cca | rnt | Mettu_1645 | Mettu_2881 | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases | Ribonuclease T; Trims short 3’ overhangs of a variety of RNA species, leaving a one or two nucleotide 3’ overhang. Responsible for the end-turnover of tRNA- specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis | 0.823 |
