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yacG protein (Methylobacter tundripaludum) - STRING interaction network
"yacG" - DNA gyrase inhibitor YacG in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
yacGDNA gyrase inhibitor YacG ; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (68 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (877 aa)
       
 
  0.930
gyrB
DNA gyrase subunit B ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (821 aa)
       
 
  0.928
zapD
Z ring-associated protein D ; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (256 aa)
         
  0.894
Mettu_2520
Type 4 prepilin-like proteins leader peptide-processing enzyme ; Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (300 aa)
              0.882
coaE
Dephosphocoenzyme A kinase ; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A (200 aa)
              0.882
parC
Topoisomerase IV subunit A ; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule (743 aa)
       
 
  0.858
parE
Topoisomerase IV subunit B ; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule (630 aa)
       
 
  0.849
Mettu_2522
Type IV-A pilus assembly ATPase PilB (570 aa)
              0.739
Mettu_2521
Type II secretion system F domain protein (406 aa)
              0.736
Mettu_1382
Type IV pilus biogenesis protein (151 aa)
 
          0.575
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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