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aroE protein (Methylobacter tundripaludum) - STRING interaction network
"aroE" - Shikimate dehydrogenase in Methylobacter tundripaludum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
aroEShikimate dehydrogenase (NADP(+)) ; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (277 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase ; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (174 aa)
  0.999
aroQ
Type II DHQase ; Catalyzes a trans-dehydration via an enolate intermediate (148 aa)
 
 
  0.998
aroB
3-dehydroquinate synthase (360 aa)
 
  0.996
aroC
5-enolpyruvylshikimate-3-phosphate phospholyase ; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (362 aa)
 
  0.984
Mettu_2827
3-phosphoshikimate 1-carboxyvinyltransferase ; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate (733 aa)
 
  0.958
Mettu_2825
Chorismate mutase (361 aa)
 
  0.948
Mettu_0758
Glutamate synthase (Ferredoxin) (1539 aa)
   
 
  0.879
Mettu_4255
Para-aminobenzoate synthase, subunit I (462 aa)
 
 
  0.866
Mettu_2539
Putative uncharacterized protein (177 aa)
              0.859
mutL
DNA mismatch repair protein MutL ; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (614 aa)
   
   
  0.798
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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