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sbcD protein (Methylobacter tundripaludum) - STRING interaction network
"sbcD" - Nuclease SbcCD subunit D in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDNuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3’->5’ double strand exonuclease that can open hairpins. It also has a 5’ single-strand endonuclease activity (413 aa)    
Predicted Functional Partners:
Mettu_2609
PFAM- RecF/RecN/SMC protein, N-terminal; KEGG- mxa-MXAN_0959 nuclease SbcCD subunit C (1260 aa)
  0.997
Mettu_3842
PFAM- RecF/RecN/SMC protein, N-terminal; KEGG- xbo-XBJ1_1690 ATP-dependent dsDNA exonuclease (1147 aa)
  0.987
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
   
  0.956
Mettu_1970
KEGG- plu-plu1837 hypothetical protein (578 aa)
   
  0.908
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (345 aa)
   
  0.904
Mettu_2674
TIGRFAM- DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM- RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG- mca-MCA1868 ATP-dependent DNA helicase RecQ; SMART- DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain (712 aa)
   
  0.804
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (614 aa)
     
 
  0.777
Mettu_2681
SNF2-related protein; KEGG- hch-HCH_06999 SNF2 family DNA/RNA helicase; PFAM- SNF2-related; Zinc finger, SWIM-type; DNA/RNA helicase, C-terminal; SMART- DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal (1083 aa)
 
 
 
  0.759
Mettu_1083
KEGG- pmy-Pmen_0549 sporulation domain-containing protein; PFAM- Sporulation/cell division region, bacteria; SMART- ATPase, AAA+ type, core (628 aa)
   
  0.749
Mettu_1189
KEGG- eba-p1B285 hypothetical protein (293 aa)
     
  0.743
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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