Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Ribosomal protein L11 methyltransferase ; Methylates ribosomal protein L11 (292 aa)
Predicted Functional Partners:
Chaperone protein DnaJ ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (376 aa)
Putative uncharacterized protein (172 aa)
50S ribosomal protein L11 ; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors (143 aa)
Methyltransferase small (398 aa)
Putative uncharacterized protein (62 aa)
tRNA-dihydrouridine synthase B ; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines (327 aa)
DNA-binding protein Fis ; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (94 aa)
Putative uncharacterized protein (175 aa)
Type II DHQase ; Catalyzes a trans-dehydration via an enolate intermediate (148 aa)
Acetyl-CoA carboxylase, biotin carboxyl carrier protein (145 aa)
Your Current Organism:
NCBI taxonomy Id: 697282 Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96