• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
tpiA protein (Methylobacter tundripaludum) - STRING interaction network
"tpiA" - Triosephosphate isomerase in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (248 aa)    
Predicted Functional Partners:
Mettu_2432
TIGRFAM- Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG- nhl-Nhal_3449 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM- Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family (337 aa)
  0.999
pgk
HAMAP- Phosphoglycerate kinase; KEGG- nwa-Nwat_0282 phosphoglycerate kinase; PFAM- Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family (390 aa)
  0.999
Mettu_2643
TIGRFAM- Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Ketose-bisphosphate aldolase, class-II; KEGG- pay-PAU_00879 fructose-bisphosphate aldolase; PFAM- Ketose-bisphosphate aldolase, class-II (359 aa)
   
 
  0.998
eno
Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (426 aa)
 
  0.995
pgi
HAMAP- Phosphoglucose isomerase (PGI); KEGG- chu-CHU_0472 glucose-6-phosphate isomerase; PFAM- Phosphoglucose isomerase (PGI); Belongs to the GPI family (545 aa)
 
  0.990
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (329 aa)
 
 
  0.946
Mettu_1557
KEGG- mca-MCA0607 phosphoglucomutase; PFAM- Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal (544 aa)
     
 
  0.915
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (328 aa)
 
 
  0.914
Mettu_1370
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (661 aa)
   
  0.902
Mettu_4376
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family (550 aa)
   
 
  0.900
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (12%) [HD]