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queE protein (Methylobacter tundripaludum) - STRING interaction network
"queE" - 7-carboxy-7-deazaguanine synthase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds (213 aa)    
Predicted Functional Partners:
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)); Belongs to the QueC family (225 aa)
 
 
  0.999
Mettu_0299
PFAM- 6-pyruvoyl tetrahydropterin synthase-related; KEGG- mca-MCA2527 6-pyruvoyl tetrahydropterin synthase, putative (134 aa)
 
   
  0.946
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1); Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily (129 aa)
 
   
  0.893
Mettu_3543
KEGG- mca-MCA1230 OmpA family protein; TIGRFAM- Peptidoglycan-associated lipoprotein; PFAM- Outer membrane protein, OmpA/MotB, C-terminal; Belongs to the ompA family (191 aa)
              0.889
cpoB
Cell division coordinator CpoB; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division (285 aa)
              0.889
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1’ of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1’ of the ribose to form th [...] (371 aa)
       
  0.877
tolB
Protein TolB; Involved in the TonB-independent uptake of proteins (427 aa)
 
          0.797
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (355 aa)
         
  0.778
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (528 aa)
         
  0.757
queA
S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (339 aa)
 
 
  0.746
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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