• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
thrS protein (Methylobacter tundripaludum) - STRING interaction network
"thrS" - Threonine--tRNA ligase in Methylobacter tundripaludum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrSThreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (635 aa)    
Predicted Functional Partners:
leuS
Leucine--tRNA ligase; TIGRFAM- Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; KEGG- tgr-Tgr7_2279 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (832 aa)
 
 
  0.954
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily (672 aa)
   
 
  0.954
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (156 aa)
 
 
  0.953
pheS
TIGRFAM- Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP- Phenylalanyl-tRNA synthetase alpha chain; KEGG- mca-MCA0697 phenylalanyl-tRNA synthetase subunit alpha; PFAM- Phenylalanyl-tRNA synthetase alpha chain; Phenylalanyl-tRNA synthetase, class II, N-terminal; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily (339 aa)
   
  0.951
pheT
TIGRFAM- Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; HAMAP- Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; KEGG- mca-MCA0698 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (791 aa)
   
  0.943
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; Belongs to the universal ribosomal protein uS5 family (168 aa)
   
  0.939
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (120 aa)
   
  0.935
serS
Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (423 aa)
 
 
  0.931
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (216 aa)
   
  0.931
lysS
Lysine--tRNA ligase; PFAM- Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM- Lysyl-tRNA synthetase, class II; HAMAP- Lysyl-tRNA synthetase; KEGG- nhl-Nhal_2437 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family (499 aa)
   
 
  0.930
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (17%) [HD]