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folE protein (Methylobacter tundripaludum) - STRING interaction network
"folE" - PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase in Methylobacter tundripaludum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
folEPFAM- GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM- GTP cyclohydrolase I; HAMAP- GTP cyclohydrolase I; KEGG- mca-MCA1670 GTP cyclohydrolase I (180 aa)    
Predicted Functional Partners:
Mettu_1611
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (119 aa)
   
 
  0.988
Mettu_2457
TIGRFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG- mca-MCA2313 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM- 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (167 aa)
   
  0.962
ribA
GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5’-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family (202 aa)
 
 
 
  0.947
Mettu_0901
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (361 aa)
       
  0.939
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (367 aa)
   
 
  0.925
Mettu_0299
PFAM- 6-pyruvoyl tetrahydropterin synthase-related; KEGG- mca-MCA2527 6-pyruvoyl tetrahydropterin synthase, putative (134 aa)
   
 
  0.887
Mettu_2918
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (303 aa)
 
 
  0.872
Mettu_1576
Outer membrane adhesin like proteiin; TIGRFAM- VCBS repeat domain; PFAM- Putative Ig; KEGG- cch-Cag_1242 VCBS; SMART- Dystroglycan-type cadherin-like (6210 aa)
   
 
  0.864
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family (322 aa)
              0.865
Mettu_1727
Multi-sensor hybrid histidine kinase; TIGRFAM- PAS; PFAM- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region; KEGG- rfr-Rfer_3395 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART- Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAC motif; PAS; Tetratricopeptide repeat (1759 aa)
   
 
    0.850
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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