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infB protein (Methylobacter tundripaludum) - STRING interaction network
"infB" - Translation initiation factor IF-2 in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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infBTranslation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (877 aa)    
Predicted Functional Partners:
rpsB
30S ribosomal protein S2 (245 aa)
 
  0.989
infA
Translation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)
     
  0.988
nusA
Transcription termination/antitermination protein NusA ; Participates in both transcription termination and antitermination (505 aa)
 
 
  0.987
truB
tRNA-uridine isomerase ; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (342 aa)
 
 
  0.987
rbfA
Ribosome-binding factor A ; Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA (120 aa)
 
   
  0.983
rpsO
30S ribosomal protein S15 ; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (89 aa)
 
 
  0.970
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (223 aa)
     
  0.968
pnp
Polynucleotide phosphorylase ; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (692 aa)
 
 
  0.968
infC
Translation initiation factor IF-3 ; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (156 aa)
   
  0.966
rpsE
30S ribosomal protein S5 ; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (168 aa)
     
  0.961
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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