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thiE protein (Methylobacter tundripaludum) - STRING interaction network
"thiE" - Thiamine-phosphate synthase in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (206 aa)    
Predicted Functional Partners:
Mettu_4306
KEGG- tgr-Tgr7_2419 phosphomethylpyrimidine kinase; PFAM- Phosphomethylpyrimidine kinase type-1 (262 aa)
 
  0.999
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family (311 aa)
 
 
  0.995
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (325 aa)
 
 
  0.981
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (626 aa)
 
 
  0.964
Mettu_4307
PFAM- Outer membrane protein, OmpA/MotB, C-terminal; KEGG- lba-Lebu_1574 OmpA/MotB domain protein; Belongs to the ompA family (288 aa)
              0.845
nnrD
Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family (487 aa)
       
  0.827
Mettu_0660
Multi-sensor hybrid histidine kinase; TIGRFAM- PAS; PFAM- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; Signal transduction response regulator, receiver region; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG- tmz-Tmz1t_2831 multi-sensor hybrid histidine kinase; SMART- ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; PAS; PAC motif (1187 aa)
   
 
    0.814
Mettu_1576
Outer membrane adhesin like proteiin; TIGRFAM- VCBS repeat domain; PFAM- Putative Ig; KEGG- cch-Cag_1242 VCBS; SMART- Dystroglycan-type cadherin-like (6210 aa)
       
    0.808
Mettu_0233
Multi-sensor signal transduction multi-kinase; PFAM- ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase-like domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG- putative phytochrome sensor protein; SMART- ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region (1710 aa)
       
    0.808
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; PFAM- Aminotransferase class-III; TIGRFAM- Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP- Glutamate-1-semialdehyde 2,1-aminomutase; KEGG- alv-Alvin_0103 glutamate-1-semialdehyde-2,1-aminomutase (426 aa)
 
   
  0.805
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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