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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
MBM_08258Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (154 aa)    
Predicted Functional Partners:
MBM_02697
Nucleoside diphosphate kinase.
  
 0.985
MBM_03955
Adenine phosphoribosyltransferase.
  
 0.969
MBM_03468
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.966
MBM_00859
GMP synthase.
  
 
 0.960
MBM_05290
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 0.947
MBM_02589
Putative dUTPase (Dut).
  
 0.933
MBM_04957
Guanylate kinase.
  
 
 0.933
MBM_02548
Bifunctional purine biosynthesis protein.
     
 0.931
MBM_04346
AMP deaminase 3.
    
 0.924
MBM_08731
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.915
Your Current Organism:
Marssonina brunnea
NCBI taxonomy Id: 1072389
Other names: M. brunnea f. sp. 'multigermtubi' MB_m1, Marssonina brunnea f. sp. 'multigermtubi' MB_m1
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