STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW01307.1PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310:IPR012309; KEGG: cpi:Cpin_6857 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase, central; ATP dependent DNA ligase, C-terminal; SPTR: ATP dependent DNA ligase. (544 aa)    
Predicted Functional Partners:
AEW01306.1
Hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: cpi:Cpin_6856 hypothetical protein; SPTR: Putative uncharacterized protein.
 0.994
AEW02583.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.957
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.952
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.913
ligA-2
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.913
AEW01337.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: cpi:Cpin_6865 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
 
   
 0.810
AEW01310.1
ATP dependent helicase, Lhr family; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase; COGs: COG1201 Lhr-like helicase; InterPro IPR011545:IPR001650:IPR013701:IPR014001; KEGG: cpi:Cpin_6864 DEAD/H associated domain protein; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/H associated domain protein.
 
    0.805
AEV96966.1
PFAM: PHP domain; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR002054:IPR003141:IPR004013; KEGG: cpi:Cpin_2044 PHP domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; DNA-directed DNA polymerase, family X; SPTR: PHP domain protein.
  
 0.775
AEV98636.1
PFAM: PHP domain; COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013:IPR002054:IPR003583:IPR003141; KEGG: sul:SYO3AOP1_1323 PHP domain protein; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase, family X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase beta family.
  
 0.775
AEW02635.1
3'-5' exonuclease, PolB; PFAM: Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; InterPro IPR019288; KEGG: rbi:RB2501_05965 hypothetical protein; PFAM: 3'-5' exonuclease, PolB-like; SPTR: Putative uncharacterized protein.
   
 0.746
Your Current Organism:
Niastella koreensis
NCBI taxonomy Id: 700598
Other names: N. koreensis GR20-10, Niastella koreensis DSM 17620, Niastella koreensis GR20-10, Niastella koreensis NBRC 106392, Niastella koreensis str. GR20-10, Niastella koreensis strain GR20-10
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