| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO49445.1 | ADO49446.1 | Entcl_3199 | Entcl_3200 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | 0.999 |
| ADO49445.1 | ADO49447.1 | Entcl_3199 | Entcl_3201 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | KEGG: kva:Kvar_3756 2,3-dihydroxybenzoate-AMP ligase; TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase. | 0.999 |
| ADO49445.1 | ADO49448.1 | Entcl_3199 | Entcl_3202 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | KEGG: kpn:KPN_00611 isochorismate synthase; TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like. | 0.983 |
| ADO49445.1 | ADO49449.1 | Entcl_3199 | Entcl_3203 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | PFAM: periplasmic binding protein; KEGG: sfv:SFV_0540 iron-enterobactin transporter periplasmic binding protein. | 0.888 |
| ADO49445.1 | ADO49454.1 | Entcl_3199 | Entcl_3208 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | Amino acid adenylation domain protein; KEGG: kpe:KPK_3973 enterobactin synthase subunit F; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase. | 0.992 |
| ADO49445.1 | ADO49455.1 | Entcl_3199 | Entcl_3209 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | PFAM: MbtH domain protein; KEGG: cro:ROD_05951 enterochelin esterase (ferric enterobactin esterase). | 0.769 |
| ADO49445.1 | ADO49456.1 | Entcl_3199 | Entcl_3210 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | PFAM: esterase; KEGG: cko:CKO_02577 enterobactin/ferric enterobactin esterase. | 0.811 |
| ADO49445.1 | ADO49457.1 | Entcl_3199 | Entcl_3211 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | KEGG: cro:ROD_05931 ferrienterobactin TonB-dependent receptor (enterobactin outer-membrane receptor); TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug. | 0.795 |
| ADO49445.1 | ADO49458.1 | Entcl_3199 | Entcl_3212 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: sec:SC0615 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Belongs to the P-Pant transferase superfamily. | 0.976 |
| ADO49445.1 | entH | Entcl_3199 | Entcl_3198 | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | Thioesterase superfamily protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 0.972 |
| ADO49446.1 | ADO49445.1 | Entcl_3200 | Entcl_3199 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | Short-chain dehydrogenase/reductase SDR; KEGG: enc:ECL_03105 2,3-dihydroxybenzoate-2,3-dehydrogenase; manually curated; PFAM: short-chain dehydrogenase/reductase SDR. | 0.999 |
| ADO49446.1 | ADO49447.1 | Entcl_3200 | Entcl_3201 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | KEGG: kva:Kvar_3756 2,3-dihydroxybenzoate-AMP ligase; TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase. | 0.999 |
| ADO49446.1 | ADO49448.1 | Entcl_3200 | Entcl_3202 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | KEGG: kpn:KPN_00611 isochorismate synthase; TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like. | 0.999 |
| ADO49446.1 | ADO49449.1 | Entcl_3200 | Entcl_3203 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | PFAM: periplasmic binding protein; KEGG: sfv:SFV_0540 iron-enterobactin transporter periplasmic binding protein. | 0.993 |
| ADO49446.1 | ADO49454.1 | Entcl_3200 | Entcl_3208 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | Amino acid adenylation domain protein; KEGG: kpe:KPK_3973 enterobactin synthase subunit F; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase. | 0.999 |
| ADO49446.1 | ADO49455.1 | Entcl_3200 | Entcl_3209 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | PFAM: MbtH domain protein; KEGG: cro:ROD_05951 enterochelin esterase (ferric enterobactin esterase). | 0.992 |
| ADO49446.1 | ADO49456.1 | Entcl_3200 | Entcl_3210 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | PFAM: esterase; KEGG: cko:CKO_02577 enterobactin/ferric enterobactin esterase. | 0.979 |
| ADO49446.1 | ADO49457.1 | Entcl_3200 | Entcl_3211 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | KEGG: cro:ROD_05931 ferrienterobactin TonB-dependent receptor (enterobactin outer-membrane receptor); TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug. | 0.846 |
| ADO49446.1 | ADO49458.1 | Entcl_3200 | Entcl_3212 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: sec:SC0615 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Belongs to the P-Pant transferase superfamily. | 0.998 |
| ADO49446.1 | entH | Entcl_3200 | Entcl_3198 | Isochorismatase; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; PFAM: isochorismatase hydrolase; phosphopantetheine-binding. | Thioesterase superfamily protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 0.981 |