| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO49814.1 | ADO49818.1 | Entcl_3573 | Entcl_3577 | SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: enc:ECL_00965 serine endoprotease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | 0.407 |
| ADO49814.1 | dgt | Entcl_3573 | Entcl_3574 | SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: enc:ECL_00965 serine endoprotease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | 0.506 |
| ADO49818.1 | ADO49814.1 | Entcl_3577 | Entcl_3573 | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: enc:ECL_00965 serine endoprotease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. | 0.407 |
| ADO49818.1 | btuF | Entcl_3577 | Entcl_3576 | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.802 |
| ADO49818.1 | dgt | Entcl_3577 | Entcl_3574 | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | 0.670 |
| ADO49818.1 | mtnN | Entcl_3577 | Entcl_3575 | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.798 |
| btuF | ADO49818.1 | Entcl_3576 | Entcl_3577 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | 0.802 |
| btuF | dgt | Entcl_3576 | Entcl_3574 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | 0.575 |
| btuF | mtnN | Entcl_3576 | Entcl_3575 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.826 |
| dgt | ADO49814.1 | Entcl_3574 | Entcl_3573 | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: enc:ECL_00965 serine endoprotease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. | 0.506 |
| dgt | ADO49818.1 | Entcl_3574 | Entcl_3577 | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | 0.670 |
| dgt | btuF | Entcl_3574 | Entcl_3576 | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.575 |
| dgt | mtnN | Entcl_3574 | Entcl_3575 | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.582 |
| mtnN | ADO49818.1 | Entcl_3575 | Entcl_3577 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | PFAM: Uncharacterised protein family UPF0126; KEGG: kva:Kvar_4209 protein of unknown function UPF0126. | 0.798 |
| mtnN | btuF | Entcl_3575 | Entcl_3576 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.826 |
| mtnN | dgt | Entcl_3575 | Entcl_3574 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. | 0.582 |