STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NrdFRibonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (321 aa)    
Predicted Functional Partners:
NrdE
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 0.999
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.932
cmk
Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.
    
 0.931
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM PF03328; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
     
 0.930
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.913
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.911
CUW_1602
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.900
CUW_1846
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.577
CUW_1848
Glycine radical domain protein; Identified by match to protein family HMM PF01228.
  
 
 0.577
CUW_1844
ATP cone domain protein; Identified by match to protein family HMM PF03477.
  
 
 0.562
Your Current Organism:
Turicibacter sanguinis
NCBI taxonomy Id: 702450
Other names: T. sanguinis PC909, Turicibacter sanguinis PC909, Turicibacter sanguinis str. PC909, Turicibacter sanguinis strain PC909, Turicibacter sp. PC909
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.