STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J9K800_ACYPIRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (802 aa)    
Predicted Functional Partners:
J9K470_ACYPI
Thymidylate_kin domain-containing protein.
  
 
 0.951
J9M062_ACYPI
Uncharacterized protein.
    
 0.951
J9JYR4_ACYPI
Guanylate kinase-like domain-containing protein.
     
 0.937
J9K1R7_ACYPI
UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
    
 0.936
Adk3
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
    
 0.935
J9K177_ACYPI
Uncharacterized protein.
  
 0.898
X1WJ13_ACYPI
Uncharacterized protein.
  
 0.897
J9L837_ACYPI
Uncharacterized protein.
  
 0.879
J9JJ96_ACYPI
Glutaredoxin domain-containing protein.
  
 0.811
ACYPI004968
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily.
   
 
  0.796
Your Current Organism:
Acyrthosiphon pisum
NCBI taxonomy Id: 7029
Other names: A. pisum, Acyrthosiphum pisum, pea aphid
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