STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0013300aa long hypothetical quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (300 aa)    
Predicted Functional Partners:
PH0011
283aa long hypothetical nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
 0.999
PH0015
464aa long hypothetical L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.999
PH0947
249aa long hypothetical protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. Belongs to the sirtuin family. Class III subfamily.
     
 0.811
PH0012
269aa long hypothetical protein.
       0.773
PH0114
316aa long hypothetical molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
 0.753
PH0182
257aa long hypothetical NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.651
PH0014
395aa long hypothetical protein.
       0.641
PH0847
287aa long hypothetical dihydrodipicoline synthase; Similar to Swiss_Prot:P39359 percent identity: 34.386 in 289aa; owl:ECAE0001348 percent identity: 35.448 in 272aa; PIR:E64330 percent identity: 40.664 in 249aa; Belongs to the DapA family.
 
  
 0.556
PH0016
475aa long hypothetical protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
       0.551
PH0642
262aa long hypothetical protein; Similar to owl:PBU4258077 percent identity:40.397 in 157aa; owl:HPAE0005494 percent identity:38.136 in 257aa; Swiss_Prot:P55176 percent identity:32.540 in 265aa. motif=ATP/GTP-binding site motif A (P-loop).
     
 0.536
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.