STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0157345aa long hypothetical transport-ATP binding protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family. (345 aa)    
Predicted Functional Partners:
PH0154
248aa long hypothetical transport system protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
 0.999
PH0151
340aa long hypothetical protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate (By similarity).
 
  
  0.919
PH0505
324aa long hypothetical oligopeptide transport ATP-binding protein AppF; Similar to Swiss_Prot:P42065 percent identity: 45.763 in 302aa; Swiss_Prot:P26905 percent identity: 43.269 in 319aa; owl:RSPNGR2342 percent identity: 40.064 in 318aa. motif=ABC transporters family signature; ATP/GTP-binding site motif A (P-loop).
 
     
0.899
PH0155
317aa long hypothetical protein; Similar to PIR:B64511 percent identity: 41.026 in 209aa; PIR:C64511 percent identity: 55.455 in 114aa. motif=ATP/GTP-binding site motif A (P-loop).
 
     0.819
PH0156
241aa long hypothetical protein; Similar to PIR:D64511 percent identity: 33.641 in 228aa.
       0.774
PH1605
425aa long hypothetical protein.
      
 0.774
PH1754
468aa long hypothetical preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move inde [...]
      
 0.769
PH0289
169aa long hypothetical protein; Similar to PIR:B64495 percent identity:36.170 in 94aa; Belongs to the GbsR family.
      
 0.650
PH0825
156aa long hypothetical protein; Belongs to the GbsR family.
      
 0.650
PH0930
413aa long hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
      
 0.649
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.