node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PH0239 | PH0240 | gene:9377155 | gene:9377156 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.993 |
PH0239 | PH0316 | gene:9377155 | gene:9377234 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 334aa long hypothetical phosphoribosylformylglycinamide cyclo-ligase; Similar to PIR:D64325 percent identity: 55.738 in 317aa; Swiss_Prot:P12043 percent identity: 42.679 in 335aa; Swiss_Prot:P43848 percent identity: 43.279 in 317aa. | 0.983 |
PH0239 | PH0318 | gene:9377155 | gene:9377237 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 433aa long hypothetical phosphoribosylglycinamide formyl transferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.913 |
PH0239 | PH0320 | gene:9377155 | gene:9377239 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 177aa long hypothetical phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
PH0239 | PH0323 | gene:9377155 | gene:9377242 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 438aa long hypothetical phosphoribosylamide--glycine ligase; Similar to PIR:A64417 percent identity: 55.478 in 442aa; owl:HUMRPS4 percent identity: 33.738 in 424aa; Swiss_Prot:P12039 percent identity: 33.819 in 352aa. motif=prokaryotic membrane lipoprotein lipid attachment site. | 0.986 |
PH0239 | PH0438 | gene:9377155 | gene:9377369 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 339aa long hypothetical adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.865 |
PH0239 | PH0852 | gene:9377155 | gene:9377803 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 0.999 |
PH0239 | PH1654 | gene:9377155 | gene:9378647 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 427aa long hypothetical serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.864 |
PH0239 | PH1953 | gene:9377155 | gene:9378966 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 705aa long hypothetical phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.980 |
PH0239 | PH1955 | gene:9377155 | gene:9378968 | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.978 |
PH0240 | PH0239 | gene:9377156 | gene:9377155 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 238aa long hypothetical phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to PIR:G64498 percent identity: 52.814 in 232aa; Swiss_Prot:P12046 percent identity: 49.785 in 235aa; Swiss_Prot:Q07296 percent identity: 48.214 in 227aa. motif=SAICAR synthetase signatures. | 0.993 |
PH0240 | PH0316 | gene:9377156 | gene:9377234 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 334aa long hypothetical phosphoribosylformylglycinamide cyclo-ligase; Similar to PIR:D64325 percent identity: 55.738 in 317aa; Swiss_Prot:P12043 percent identity: 42.679 in 335aa; Swiss_Prot:P43848 percent identity: 43.279 in 317aa. | 0.999 |
PH0240 | PH0318 | gene:9377156 | gene:9377237 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 433aa long hypothetical phosphoribosylglycinamide formyl transferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.957 |
PH0240 | PH0320 | gene:9377156 | gene:9377239 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 177aa long hypothetical phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
PH0240 | PH0323 | gene:9377156 | gene:9377242 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 438aa long hypothetical phosphoribosylamide--glycine ligase; Similar to PIR:A64417 percent identity: 55.478 in 442aa; owl:HUMRPS4 percent identity: 33.738 in 424aa; Swiss_Prot:P12039 percent identity: 33.819 in 352aa. motif=prokaryotic membrane lipoprotein lipid attachment site. | 0.999 |
PH0240 | PH0438 | gene:9377156 | gene:9377369 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 339aa long hypothetical adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.815 |
PH0240 | PH0852 | gene:9377156 | gene:9377803 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 450aa long hypothetical adenylosuccinate lyase; Similar to PIR:A64416 percent identity: 58.864 in 443aa; Swiss_Prot:P12047 percent identity: 42.373 in 419aa; owl:S76222 percent identity: 41.769 in 414aa. motif=fumarate lyases signature. | 0.993 |
PH0240 | PH1654 | gene:9377156 | gene:9378647 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 427aa long hypothetical serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.898 |
PH0240 | PH1953 | gene:9377156 | gene:9378966 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 705aa long hypothetical phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.999 |
PH0240 | PH1955 | gene:9377156 | gene:9378968 | 449aa long hypothetical amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 227aa long hypothetical phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.998 |