STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0373230aa long hypothetical cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (230 aa)    
Predicted Functional Partners:
PH0372
181aa long hypothetical protein.
 
  
 0.990
PH0075
175aa long hypothetical cob(I)alamin adenosyltransferase; Similar to Swiss_Prot:P13040 percent identity: 33.140 in 172aa; Swiss_Prot:P31570 percent identity: 31.395 in 172aa; PIR:S75074 percent identity: 38.506 in 177aa.
 
 
 0.975
PH0671
172aa long hypothetical protein; Similar to Swiss_Prot:P45515 percent identity:42.500 in 167aa; owl:KPU309038 percent identity:41.875 in 167aa.
    
 0.947
PH0376
283aa long hypothetical cobalamin biosynthesis protein D; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.921
PH0034
335aa long hypothetical protein; Similar to PIR:E64499 percent identity: 38.835 in 323aa; PIR:S74983 percent identity: 34.568 in 341aa; Belongs to the UPF0284 family.
 
  
 0.823
PH0471
143aa long hypothetical protein.
  
    0.820
PH0377
328aa long hypothetical histidinol-phosphate aminotransferase; Similar to Swiss_Prot:P17736 percent identity:32.105 in 202aa; PIR:D64187 percent identity:29.293 in 215aa. motif=aminotransferases class-II pyridoxal-phosphate attachment site.
 
   
 0.818
PH0374
147aa long hypothetical protein; Similar to PIR:A64466 percent identity: 51.754 in 127aa.
    
  0.796
PH0375
221aa long hypothetical protein; Similar to PIR:B64371 percent identity:29.000 in 210aa.
       0.609
PH0814
199aa long hypothetical protein.
 
   
 0.609
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.