STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH04521127aa long hypothetical ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity); Belongs to the peptidase S16 family. Archaeal LonB subfamily. (1127 aa)    
Predicted Functional Partners:
PH0017
549aa long hypothetical thermophilic factor; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 
 0.902
PH1842
172aa long hypothetical protein; Similar to owl:WHTHSP169C percent identity:37.864 in 104aa; owl:OSU81385 percent identity:37.864 in 104aa; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.896
PH0451
122aa long hypothetical protein.
 
   
 0.793
PH1899
735aa long hypothetical elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation facto [...]
 
 
 0.695
PH0482
120aa long hypothetical chemotaxis protein (cheY); Similar to owl:TMU305014 percent identity: 71.304 in 115aa; Swiss_Prot:P24072 percent identity: 62.393 in 117aa; owl:LMCHE percent identity: 54.310 in 116aa.
     
 0.689
PH1545
907aa long hypothetical DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
   
 0.689
PH1699
447aa long hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
  
 0.669
PH0965
967aa long hypothetical leucyl-tRNA synthetase; Similar to PIR:A64379 percent identity: 53.987 in 980aa; owl:F21M12 percent identity: 36.017 in 737aa; Swiss_Prot:Q09996 percent identity: 34.910 in 766aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
  
 
 0.660
PH1116
582aa long hypothetical protein; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
 
    0.660
PH0063
254aa long hypothetical protein.
       0.654
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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