STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0710460aa long hypothetical seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (460 aa)    
Predicted Functional Partners:
PH1478
629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
 
 
 0.937
PH1921
301aa long hypothetical tryptophanyl-tRNA synthetase; Similar to owl:S51901 percent identity: 49.296 in 298aa; Swiss_Prot:Q09692 percent identity: 48.352 in 286aa; Swiss_Prot:P23381 percent identity: 46.831 in 301aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.932
PH0314
896aa long hypothetical valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.930
PH0636
476aa long hypothetical cysteinyl-tRNA synthetase; Similar to Swiss_Prot:Q06752 percent identity: 48.707 in 473aa; Swiss_Prot:P43816 percent identity: 50.000 in 472aa; Swiss_Prot:P21888 percent identity: 48.904 in 474aa.
 
 
 0.918
PH1011
375aa long hypothetical tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
 
  
 0.914
PH1614
570aa long hypothetical glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly).
   
  
 0.902
PH0290
431aa long hypothetical histidyl-tRNA synthetase; Similar to PIR:G64424 percent identity: 45.854 in 425aa; owl:HPAE0006251 percent identity: 33.577 in 418aa; Swiss_Prot:P46220 percent identity: 46.617 in 133aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.889
PH0699
625aa long hypothetical threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.874
PH1686
570aa long hypothetical glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
  
 0.872
PH0993
723aa long hypothetical methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.861
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.