STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0769414aa long hypothetical cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (414 aa)    
Predicted Functional Partners:
PH0768
256aa long hypothetical SOJ protein; Similar to PIR:G64512 percent identity: 52.174 in 258aa; Swiss_Prot:P37522 percent identity: 38.153 in 250aa; PIR:S72958 percent identity: 15.415 in 254aa.
  
  
 0.960
PH1986
293aa long hypothetical protein; Involved in protein export.
   
  
 0.806
PHS024
62aa long hypothetical protein; Similar to PIR:E64509 percent identity: 28.571 in 49aa; PIR:E64368 percent identity: 36.364 in 55aa; Swiss_Prot:P28910 percent identity:44.186 in 43aa.
     
 0.772
PH1484
428aa long hypothetical elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
  
 0.720
PH1985
507aa long hypothetical protein; Involved in protein export.
  
  
 0.649
PH1987
324aa long hypothetical O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
     
 0.601
PH0290
431aa long hypothetical histidyl-tRNA synthetase; Similar to PIR:G64424 percent identity: 45.854 in 425aa; owl:HPAE0006251 percent identity: 33.577 in 418aa; Swiss_Prot:P46220 percent identity: 46.617 in 133aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.584
PH1781
134aa long hypothetical protein.
   
 
 0.547
PH0770
154aa long hypothetical protein; Motif=mitochondrial energy transfer proteins signature.
       0.509
PH1899
735aa long hypothetical elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation facto [...]
 
 
 0.503
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.