STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0847287aa long hypothetical dihydrodipicoline synthase; Similar to Swiss_Prot:P39359 percent identity: 34.386 in 289aa; owl:ECAE0001348 percent identity: 35.448 in 272aa; PIR:E64330 percent identity: 40.664 in 249aa; Belongs to the DapA family. (287 aa)    
Predicted Functional Partners:
PH1088
334aa long hypothetical aspartate-semialdehyde dehydrogenase; Similar to PIR:F64325 percent identity: 50.000 in 343aa; Swiss_Prot:P41394 percent identity: 45.092 in 345aa; owl:D89129 percent identity: 43.844 in 353aa.
 
 
 0.983
PH1075
319aa long hypothetical homoserine dehydrogenase; Similar to PIR:A64500 percent identity: 34.967 in 329aa.
 
 
 0.960
PH0858
359aa long hypothetical protein; Similar to PIR:C64371 percent identity:43.558 in 169aa. motif=aspartokinase signature; Belongs to the aspartokinase family.
 
  
 0.860
PH1071
450aa long hypothetical protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
 
  
 0.760
PH0058
158aa long hypothetical 40S ribosomal protein S13; Similar to Swiss_Prot:P54012 percent identity: 70.667 in 157aa; Swiss_Prot:Q05761 percent identity: 50.000 in 157aa; Swiss_Prot:P49203 percent identity: 48.649 in 155aa. motif=ribosomal protein S15 signature.
  
    0.722
PH1772
210aa long hypothetical 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
  
 0.717
PH1086
346aa long hypothetical aspartokinase; Similar to Swiss_Prot:P26512 percent identity:34.375 in 130aa; PIR:C64371 percent identity:35.948 in 157aa; OWL:TTHASKAB percent identity:32.308 in 131aa. motif=aspartokinase signature.
 
  
 0.692
PH1899
735aa long hypothetical elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation facto [...]
  
  
 0.667
PH1541
218aa long hypothetical 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center (By similarity); Belongs to the universal ribosomal protein uS7 family.
   
  
 0.655
PH1716
366aa long hypothetical acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
     
 0.645
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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