STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH0961275aa long hypothetical translation initiation factor eIF-2 alpha chain; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family. (275 aa)    
Predicted Functional Partners:
PH0060
199aa long hypothetical 30S ribosomal protein S3a; Similar to Swiss_Prot:P54059 percent identity: 41.579 in 190aa; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.999
PH0605
140aa long hypothetical translation initiation factor eIF-2 beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
   
 0.999
PH1568
116aa long hypothetical translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
  
 0.999
PH1706
411aa long hypothetical translation initiation factor eIF-2 gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
 0.999
PH1772
210aa long hypothetical 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.999
PH1766
243aa long hypothetical 30S ribosomal protein S4; Similar to Swiss_Prot:P54039 percent identity: 52.720 in 247aa; Swiss_Prot:P14023 percent identity: 47.280 in 247aa; GENPEPT:Y07778 percent identity: 36.752 in 238aa. motif=ribosomal protein S4e signature; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.998
PH1774
132aa long hypothetical 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.998
PH0615
125aa long hypothetical 30S ribosomal protein S6E; Similar to Swiss_Prot:P54067 percent identity: 64.545 in 124aa. motif=ribosomal protein S6e signature; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.997
PH1757
236aa long hypothetical 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
 0.997
PH1764
130aa long hypothetical 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 0.997
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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