STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1006480aa long hypothetical prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa)    
Predicted Functional Partners:
PHS043
99aa long hypothetical 50S ribosomal protein L30; Similar to Swiss_Prot:P29160 percent identity: 70.833 in 96aa; Swiss_Prot:P54061 percent identity: 50.505 in 99aa; Swiss_Prot:P11522 percent identity: 50.538 in 93aa. motif=ribosomal protein L30e signatures; Belongs to the eukaryotic ribosomal protein eL30 family.
   
 0.980
PHS049
86aa long hypothetical 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
 0.980
PH1634
142aa long hypothetical 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 0.964
PHS032
97aa long hypothetical 50S ribosomal protein L21; Similar to Swiss_Prot:P54013 percent identity: 67.368 in 95aa; Swiss_Prot:P12734 percent identity: 51.163 in 86aa; GENPEPT:F20014 percent identity: 37.500 in 72aa; Belongs to the eukaryotic ribosomal protein eL21 family.
   
 0.962
PH1763
187aa long hypothetical 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 0.959
PH1758
206aa long hypothetical 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 0.958
PH1773
155aa long hypothetical 50S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 0.956
PH1761
130aa long hypothetical 50S ribosomal protein L32; Similar to Swiss_Prot:P54010 percent identity: 61.864 in 120aa; Swiss_Prot:P14549 percent identity: 47.934 in 123aa; GENPEPT:Y07778 percent identity: 43.119 in 111aa; Belongs to the eukaryotic ribosomal protein eL32 family.
   
 0.954
PHS052
87aa long hypothetical 50S ribosomal protein L35; Similar to Swiss_Prot:P20299 percent identity: 91.954 in 87aa; Swiss_Prot:P41056 percent identity: 38.095 in 92aa; Swiss_Prot:P05744 percent identity: 36.905 in 92aa. motif=ribosomal protein L35Ae signature; Belongs to the eukaryotic ribosomal protein eL33 family.
  
 0.954
PH1940
109aa long hypothetical 50S ribosomal protein L44; Binds to the 23S rRNA.
  
 0.954
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.