STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1020438aa long hypothetical aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (438 aa)    
Predicted Functional Partners:
PH0993
723aa long hypothetical methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.810
PH0965
967aa long hypothetical leucyl-tRNA synthetase; Similar to PIR:A64379 percent identity: 53.987 in 980aa; owl:F21M12 percent identity: 36.017 in 737aa; Swiss_Prot:Q09996 percent identity: 34.910 in 766aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
 
 
 0.793
PH1686
570aa long hypothetical glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
 
 0.792
PH1065
1066aa long hypothetical isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.781
PH1478
629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature.
 
 
 0.763
PH0138
466aa long hypothetical 4-aminobutyrate aminotransferase; Amino-acid racemase able to utilize a broad range of substrates. Can use Met, Leu, Phe, Ala, Ser, Ile, Val, Trp, Tyr and Thr. Is mostly active with Phe, Leu, Met and Tyr, followed by Ile, Thr and Trp. Has weaker activity with Val, Ser and Ala. Shows no activity toward Pro, Asp, Glu, Arg, His, Gln and Asn.
     
 0.726
PH1614
570aa long hypothetical glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly).
 
 
 0.713
PH0782
474aa long hypothetical 4-aminobutyrate aminotransferase; Catalyzes the interconversion of L-alanine and D-alanine, and L-serine and D-serine. Has weak activity with valine and threonine.
     
 0.654
PH1423
454aa long hypothetical 4-aminobutyrate aminotransferase; Similar to owl:D5045389 percent identity: 38.539 in 406aa; Swiss_Prot:P30268 percent identity: 39.552 in 409aa; Swiss_Prot:P40829 percent identity: 39.646 in 409aa. motif=aminotransferases class-III pyridoxal-phosphate attachment site; ATP/GTP-binding s; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.654
PH1501
438aa long hypothetical aminotransferase; Similar to owl:D5045389 percent identity: 38.287 in 401aa; Swiss_Prot:P30268 percent identity: 36.409 in 409aa; Swiss_Prot:P22256 percent identity: 36.750 in 409aa. motif=aminotransferases class-III pyridoxal-phosphate attachment site; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.654
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
Server load: low (26%) [HD]