STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PH1032330aa long hypothetical modification methylase (adenine-specific); Similar to PIR:S34414 percent identity: 49.064 in 290aa; Swiss_Prot:P50179 percent identity: 47.191 in 290aa; Swiss_Prot:P04043 percent identity: 47.015 in 291aa. motif=N-6 Adenine-specific DNA methylases signature. (330 aa)    
Predicted Functional Partners:
PH0584
309aa long hypothetical modification methylase; Similar to Swiss_Prot:Q04845 percent identity:34.034 in 249aa; PIR:A64423 percent identity:47.368 in 96aa. motif=N-4 cytosine-specific DNA methylases signature.
 
  
 0.779
PH0039
238aa long hypothetical modification methylase; Similar to PIR:C64370 percent identity: 54.867 in 234aa; PIR:G64449 percent identity: 54.825 in 237aa; owl:MKFWUGDB percent identity: 68.919 in 77aa.
     
 0.645
PH0155
317aa long hypothetical protein; Similar to PIR:B64511 percent identity: 41.026 in 209aa; PIR:C64511 percent identity: 55.455 in 114aa. motif=ATP/GTP-binding site motif A (P-loop).
 
    0.469
PH1575
287aa long hypothetical protein; Metal-dependent phosphatase with probable damage-control functions. Shows phosphatase activity against p- nitrophenyl phosphate (pNPP), but natural substrates have not been identified yet. Low phosphatase activity against 8- oxo nucleotides suggests that it could hydrolyze oxidatively damaged purine nucleotides or their biosynthetic intermediates.
     
 0.440
Your Current Organism:
Pyrococcus horikoshii
NCBI taxonomy Id: 70601
Other names: P. horikoshii OT3, Pyrococcus horikoshii OT-3, Pyrococcus horikoshii OT3, Pyrococcus horikoshii str. OT3, Pyrococcus shinkaii OT3, Pyrococcus sp. OT3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.